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Department of Health Services

Public Health Regional Laboratory

Zika, Dengue, & Chikungunya virus detection (CDC Trioplex), RT-PCR

The Trioplex Real-time RT-PCR Assay (Trioplex rRT-PCR) is intended for the qualitative detection and differentiation of RNA from Zika virus, dengue virus, and chikungunya virus in human sera or cerebrospinal fluid (each collected alongside a patientmatched serum specimen), and for the qualitative detection of Zika virus RNA in urine, and amniotic fluid (each collected alongside a patient-matched serum specimen).  For use in individuals who meet the Centers for Disease Control and Prevention (CDC) clinical and epidemiological criteria for Zika virus testing. Zika viruses are primarily transmitted by Aedes aegypti and Aedes albopictus mosquitos.

Portal Ordering Code
  • TRIO-PCR-SERUM
  • TRIO-PCR-CSF
CPT Code(s)

87662, 87798x2

Fee Schedule

Storage and Transport Criteria
Specimen Storage Specimen Transport
Acceptable Specimens
Minimum Volume
Frozen Range
-70°C - 0°C
Refrigerated Range
0.1°C - 8°C
Room Temperature Range
8.1°C - 30°C
Stability at
4°C - 25°C
Serum or CSF 1 mL ≤ -20°C upon receipt Reject Reject Dry ice or cold packs (acceptable)
Includes

CSF - Serum order choice is automatically ordered.

Methodology

RT-PCR

Assay Category

EUA (Emergency Use Authorization)

Reference Range

See laboratory report

Alternative Names
  • Trioplex Real-time RT-PCR Assay
  • Chikungunya virus
  • Dengue virus
  • ZIKA virus
Preferred Specimen(s)
  • Serum
  • CSF
Alternative Specimen(s)

N/A

Minimum Volume

1 mL 

Special Instructions

CSF - Collect serum in conjunction with CSF

Reject Criteria
  • Inadequately labeled specimens
  • Leaking specimens
  • QNS (quantities not sufficient)
  • Specimens not meeting the Storage & Transport criteria upon receipt at laboratory
Setup Schedule

Testing is performed on an as-needed basis.

Turn around time (TAT)

3 business days from arrival at the lab